Gynecology Oncology
Zahraa Al-Tamimi; Mahmood A. Al Ani
Articles in Press, Accepted Manuscript, Available Online from 11 January 2024
Abstract
Background: Asymptomatic bacteruria is a form of lower urinary tract infections (UTIs) that is significant during pregnancy for its high prevalence, high tendendency for persistence and progression to the other symptomatic forms, besides posing adverse effects on pregnancy through effects on both maternal ...
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Background: Asymptomatic bacteruria is a form of lower urinary tract infections (UTIs) that is significant during pregnancy for its high prevalence, high tendendency for persistence and progression to the other symptomatic forms, besides posing adverse effects on pregnancy through effects on both maternal and fetal morbidity. In this respect, Cranberry has been suggested in the prevention and sometimes treatment with a big conflict in results and recommendations.
Materials & Methods: In our study we tried to search its role in treatment and prevention using capsules rather than juices (the most common form in previous studies) and comparing results of its use alone versus combined with antibiotics on the outcome.
Results: Results showed that it is less effective than antibiotics in the treatment ( 56% versus 88% cure rate) (X2: 6.3492; df=l; P value =0.01174), closely effective to them in prevention (26.7% recurrence on cranberry versus 12.5% on antibiotic) (X2:0.9954;P value=0.3184), but reducing the cure rate when used in combination with antibiotics in treatment versus antibiotics alone ( 28.6% versus 57.1% response) (X2=1.1667; P value = 0.2801). Regarding the most commonly reported side effects: headache was supervening consistent with reports in previous studies, whereas gastrointestinal upset commonly experienced in cranberry juice was reported in only (8%) of study cases.
Conclusion: In view of results we recommend using cranberry especially in what seems to be less harmful formulation (capsules) in the prevention of asymptomatic bacteruria in pregnant population and discourage using it in the treatment whether alone or in combination with antibiotics.
Obstetrics and Gynecology
Alaa Abdul Hussein Kareem Al-Daamy
Volume 8, Issue 6 , November and December 2023, , Pages 620-628
Abstract
Background & Objective: Increasing urinary tract infections (UTI) in pregnant women was a reason for which this study aimed to find out the spread of bacteria in them and also study the resistance of bacteria to antibiotics and the type of resistance.Materials & Methods: During November ...
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Background & Objective: Increasing urinary tract infections (UTI) in pregnant women was a reason for which this study aimed to find out the spread of bacteria in them and also study the resistance of bacteria to antibiotics and the type of resistance.Materials & Methods: During November 2022, 50 urine samples were collected from pregnant women with symptoms of UTI. Direct microscopy tests were conducted on the samples. The samples were cultured on the media of MacConkey agar (MAC) and blood agar. Biochemical tests were performed and diagnosed using the VITEC-2 system. Antibiotic susceptibility screening test was done for all isolates.Results: Of the 50 bacterial isolates diagnosed and isolated from pregnant women with UTI, 84% were gram-negative and 16% were gram-positive. The most prevalent bacteria were E. coli, with a rate of 60%, followed by Proteus mirabilis, with a rate of 12%. All E. coli isolates were resistant (100%) to the AMOX antibiotic, and the isolates showed high resistance (87%) to CFR, CN, CZ, CXM, CAE, CPD, CRO NA and SXT antibiotics. 13.3% of E.coli isolates were extended detection and response (XDR), 50% and 25% of Staphylococcus hominis and aureus isolates were XRD, respectively.Conclusion: E. coli is the most common and most resistant bacteria of type XRD, and gram-positive bacteria, staph bacteria, showed resistance to type XRD. In addition, gram-negative bacteria showed high resistance to many antibiotics, including AMOX, CFR, CN, CZ, CXM, and CAE. Gram-positive bacteria showed complete resistance against BENPEN, OXA, CLIN, TEC, VAN, TET, FUS and VAN.
