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jogcr 2017, 2(4): 0-0 Back to browse issues page
Intraperitoneal Chemotherapy in Ovarian Cancer
Setareh Akhavan1, Nadereh Behtash1, Mohsen Esfandbod2, Mitra Moddares Gilani1, Azam-Sadat Mousavi1, Shahrzad Sheikh Hasani1
1- Gynecology Oncology Department, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
2- Hematology Oncology Department, Vali-Asr Hospital ,Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (701 Views)
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer death in women. Primary surgery, followed by adjuvant chemotherapy is the basis of treatment for this disease. A standard treatment includes primary surgery and if possible optimal debulking surgery (tumor residue of <; 1 cm), followed by a chemotherapy; paclitaxel-carboplatin is the standard regimen in ovarian cancer. Given that the main method of spreading this disease is in the peritoneal cavity, the systemic chemotherapy brings about numerous complications; moreover, as the method of prescribing a drug inside the peritoneum causes a high drug concentration in the peritoneal cavity, conducting an intraperitoneal chemotherapy has been examined clinically. In cases of ovarian cancer recurrence, performing a secondary cytoreductive surgery, in addition to hyperthermic intraperitoneal chemotherapy (HIPEC), has led to a good survival among patients. Currently, studies are ongoing to better explain the effects of this treatment method compared to previous methods.
Keywords: Epithelial Ovarian Cancer, Intraperitoneal Chemotherapy, HIPEC
Full-Text [PDF 958 kb]   (166 Downloads)    
Systematic Review: Original Research | Subject: General
Received: 2018/05/4 | Accepted: 2018/12/29 | Published: 2018/12/29
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Akhavan S, Behtash N, Esfandbod M, Moddares Gilani M, Mousavi A, Sheikh Hasani S. Intraperitoneal Chemotherapy in Ovarian Cancer . jogcr. 2017; 2 (4)
URL: http://jogcr.com/article-1-157-en.html

Volume 2, Issue 4 (12-2017) Back to browse issues page
Journal of Obstetrics, Gynecology and Cancer Research (JOGCR)
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