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Volume 4, Issue 1 (Winter 2019)                   J Obstet Gynecol Cancer Res 2019, 4(1): 24-28 | Back to browse issues page

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Borna S, Khorami N, Ghamari A, Ghotbizadeh Vahdani F. Amniotic Fluid and Maternal Lipid Profiles and Pregnancy Outcomes: Is There any Relationship?. J Obstet Gynecol Cancer Res. 2019; 4 (1) :24-28
URL: http://jogcr.com/article-1-222-en.html
1- Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran
2- Growth and Development Research Center, Children Medical Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran
3- Maternal-Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran , Fghotbi@yahoo.com
Abstract:   (8433 Views)

Background & Objective: This prospective study aimed to determine the relationship between maternal and amniotic fluid (AF) lipid profiles in the second trimester with pregnancy outcomes.
Materials & Methods: One hundred-eighty singleton pregnant women, with a gestational age of 16-22 weeks, were enrolled in this study. All women underwent amniocentesis, and 2 mL of AF was investigated for AF lipid profile. Furthermore, the serum maternal lipid profile was evaluated simultaneously.  All participants were followed up until the delivery, and postnatal outcomes were recorded.
Results: Mean maternal age and body mass index (BMI) of all participants were 5.8±33 years and 25.6±2.8 kg/m2, respectively. Mean maternal estriol, cholesterol, and triglyceride levels, as well as mean cholesterol and triglyceride levels of AF, were significantly different between term and preterm; intrauterine growth retardation (IUGR) and non-intrauterine growth retardation (non-IUGR); and low birth weight and normal weight neonates (P<0.001). The AF cholesterol level was an independent predictor of term or preterm delivery, while the maternal estriol level was an independent predictor of IUGR or normal growth.
Conclusion: Maternal and amniotic fluid lipid profiles could be good indicatives of fetus growth.

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Systematic Review: Original Research | Subject: Obstetrics and Gynecology
Received: 2018/09/16 | Accepted: 2019/02/5 | Published: 2019/03/1

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