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Volume 5, Issue 4 (Fall 2020)                   J Obstet Gynecol Cancer Res 2020, 5(4): 175-177 | Back to browse issues page


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Hasanzadeh M, Nourbakhsh S S, Jafarian A H, Malakuti P. Vaginal Adenosis in Two Patients with No History of Diethylstilbestrol: A Case Report. J Obstet Gynecol Cancer Res. 2020; 5 (4) :175-177
URL: http://jogcr.com/article-1-298-en.html
1- Department of Obstetrics and Gynecology, Fellow of Gynecology Oncology, Women’s Health Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , hasanzademofradm@mums.ac.ir
2- Medical Student, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3- Associate Professor, Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Medical Student, Faculty of Medicine, Szeged University of Medical Sciences, Szeged, Hungary
Abstract:   (64 Views)
Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis in female fetus. DES has been reported rarely with no history of fetal use.
Case Presentation: In this article, we report two vaginal adenosis patients with no history of DES during pregnancy. There was no vaginal cancer in the follow-up of the patients.
Conclusion: Vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.
Full-Text [PDF 318 kb]   (23 Downloads)    
Systematic Review: Case Report | Subject: Gynecology Oncology
Received: 2020/05/17 | Accepted: 2020/07/9 | Published: 2020/07/28

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