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Volume 7, Issue 3 (May & June 2022)                   J Obstet Gynecol Cancer Res 2022, 7(3): 5-5 | Back to browse issues page

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Eslamian L, Jamal A, marsousi V, Ahmadi M, Golbabaei A, Boustani P. Accuracy of Fetal Cardiac Function Measured by Myocardial Performance Index in Fetal Intrauterine Growth Restriction. J Obstet Gynecol Cancer Res. 2022; 7 (3) :5-5
URL: http://jogcr.com/article-1-472-en.html
1- Obstetrics & Gynecology Department, Perinatology Unit, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
2- Fellowship of Perinatology, Obstetrics and Gynecology Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran , marjan80810@yahoo.com
3- Pediatric cardiologist, Perinatology Unit, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran
4- Medical student, Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (83 Views)
Background and Objective: IUGR (intrauterine growth restriction) fetuses has been known as a significant concern in clinical practice. It is considered associated with fetal mortality and morbidity and prenatal adverse cardiac remodeling. The aim of this study is evaluation of the relation between MPI (myocardial performance index) abnormalities and doppler finding in both normal and IUGR fetuses.
Methods: In this cross-sectional study, 400 consecutive pregnant women in Shariati Hospital, Tehran, Iran, in 2019 and 2020 underwent ultrasound assessment at 28-40 weeks, in which among the 400 performed ultrasounds, 47 fetuses with IUGR were selected as a case group, and 47 fetuses with normal weight were selected based on AGA (appropriate gestational age). Cardiac function was evaluated by measuring MPI in diastolic and systolic function in two groups. The results were compared to the IUGR (case group) and control group by SPSS software.
Results: In ROC analysis, the AUC (area under the curve) for LV MPI was 0.929 (CI95%: 0.868-0.991; P=0.001), and the sensitivity and specificity values were 87% and 69.4% with cut-off point 0.2850. In ROC analysis, the area under the curve for RV MPI was 0.842 (CI95%: 0.741-0.942; P=0.001), and the sensitivity and specificity values were 78.3% and 63.9%, with a cut-off point 0.2850. Left and right ventricular MPI showed a significant difference statistically between the case and the control groups.
Conclusions: The study shows a significant rise of MPI in IUGR fetuses. MPI can be considered as a useful parameter for evaluating the severity of growth restriction in IUGR fetuses.
Systematic Review: Original Research | Subject: Maternal Fetal Medicine
Received: 2021/08/18 | Accepted: 2021/09/30 | Published: 2021/11/25

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