Document Type : Original Research Article
Authors
Department of Medical Laboratory Techniques, Al-Mussaib Technical Institute, Al-Furat Al-Awsat Technical University, 51009, Iraq
Abstract
Background & Objective: In 2020, breast cancer claimed the lives of approximately 684,996 women worldwide. The use of cancer biomarkers has greatly improved the effectiveness of treatment and early detection. The objective of this study was to identify testin as a potential biomarker.
Materials & Methods: Sixteen women participated by providing serum samples for measuring testin concentrations in Iraqi breast cancer patients. Additionally, a control group of 20 healthy individuals was selected. The testin protein concentration was detected using the serum ELISA method.
Results: A significant difference was observed between the age groups of patients and healthy women. The majority of women with breast cancer were recorded to be in their thirties to sixties, with 16 (26.7%), 21 (35%), and 19 (31.7%) cases respectively. On the other hand, there were fewer breast cancer cases recorded in the twenties, with only 1 (1.7%) case out of the total study population of 60 (100%). This difference was found to be statistically significant, with a P-value of 0.01.
Conclusion: The present study discovered that breast cancer patients have higher levels of testin compared to healthy women. There is a growing body of evidence suggesting that testin contributes to the development of breast cancer, making it an appealing protein to focus on for cancer treatment.
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