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Volume 6, Issue 3 (Summer 2021)                   J Obstet Gynecol Cancer Res 2021, 6(3): 116-121 | Back to browse issues page

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MohammadBeigi R, Fathollahpour A, Fathollahpour A, Kashanian M, Sheikhansari N. A Comparison Between Maternal and Neonatal Serum Level of Vitamin D and Its Relationship with Anthropometric Neonatal Factors. J Obstet Gynecol Cancer Res. 2021; 6 (3) :116-121
URL: http://jogcr.com/article-1-341-en.html
1- Department of Obstetrics and Gynecology, Akbarabadi Teaching Hospital, Iran University of Medical Sciences, Tehran, Iran
2- Department of Pediatrics, Pediatric Endocrinology and Metabolism, School of Medicine, Cancer and Immunology Research Center, Besat Hospital, Sanandaj, Iran
3- Department of Obstetrics and Gynecology, Akbarabadi Teaching Hospital, Iran University of Medical Sciences, Tehran, Iran , maryamkashanian@yahoo.com
4- School of Medicine, University of Exeter, Exeter, UK
Abstract:   (556 Views)

Background & Objective: The aims of present study were to compare the vitamin D concentration in pregnant women and the umbilical cord blood while investigating for a relationship between its level and anthropometric neonatal factors (i.e. birth weight, birth length, and head circumference).
Materials & Methods: The study was performed as a descriptive cross-sectional study on pregnant women who were admitted to the labor ward for delivery. Serum level of 25-hydroxyvitamin D [25(OH) D], was measured and compared in women and the umbilical cord blood. The relationship between 25(OH) D levels and anthropometric neonatal factors including birth weight, birth length and head circumference was evaluated.
Results: A total of 106 pregnant women (53 Iranians and 53 Afghan refugees’ women) were evaluated. There was a significant correlation between maternal serum level of 25(OH) D and that of their neonates, both in Iranians and Afghans considering gestational age as a confounding factor (R=0.62, P=0.000). Maternal and neonatal 25(OH) D levels were significantly higher in Iranians than Afghans (27.2±11.5 ng/mL VS 21.9±12.7 ng/mL, P=0.026 and 26.5±11.2 VS 17.3±11.4, P=0.000) respectively. However, neonatal weight and head circumference (HC), were not different in Iranians and Afghans except for neonatal height which was higher in Afghans (P=0.015) irrespective of lower amount of neonatal 25(OH) D levels.
The mean cord levels of vitamin D in boys and girls did not show a significant difference. There was no significant correlation between 25(OH) D serum level and pregnant women’s level of education, pre-labor rupture of membranes (PROM), past medical history (PMH), taking supplements and smoking.
Conclusion: Maternal and neonatal 25(OH) D levels did not influence neonatal anthropometry.

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Systematic Review: Original Research | Subject: Maternal Fetal Medicine
Received: 2021/02/9 | Accepted: 2021/03/25 | Published: 2021/06/18

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