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Volume 4, Issue 4 (Fall 2019)                   J Obstet Gynecol Cancer Res 2019, 4(4): 151-154 | Back to browse issues page

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Deldar Pasikhani M, Ghotbizadeh F, Akbari R, Shooshtari M, Pajouhi A. A Rare Case of Mortality Following Heparin-induced Necrotizing Skin Lesions as Thromboprophylaxis After Total Abdominal Hysterectomy. J Obstet Gynecol Cancer Res. 2019; 4 (4) :151-154
URL: http://jogcr.com/article-1-253-en.html
A Rare Case of Mortality Following Heparin-induced Necrotizing Skin Lesions as Thromboprophylaxis After Total Abdominal Hysterectomy
Maryam Deldar Pasikhani1, Fahimeh Ghotbizadeh *2, Razieh Akbari1 , Mahshid Shooshtari1, Atieh Pajouhi1
1- Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
2- Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran , fghotbi@yahoo.com
Abstract:   (1256 Views)

Background & Objective: Anticoagulant therapy has been used for the prevention and treatment of deep vein thrombosis and pulmonary embolism. Heparin-induced necrotizing skin lesion is a serious complication that can be potentially life-threatening.
Case Report: We report a 55-year-old female presenting with skin necrosis without thrombocytopenia after prescribing heparin prophylaxis. She had died as it was not possible to discontinue her heparin therapy.
Conclusion: Heparin-induced skin necrosis should be suspected in all patients who undergo UFH or LMWH. Observation of platelet count is recommended at the onset of skin lesions. Early diagnosis of this condition can be helpful for the management of this potentially mortal disease.

Keywords: Anticoagulants, Heparin, Necrotic Skin lesions
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Systematic Review: Case Report | Subject: Pathology
Received: 2020/02/1 | Accepted: 2020/04/28 | Published: 2020/04/28
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