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Volume 7, Issue 3 (May & June 2022)                   J Obstet Gynecol Cancer Res 2022, 7(3): 11-11 | Back to browse issues page

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behnamfar F, Nazemi M, Mohammadizadeh F. Rhabdomyosarcoma of the Cervix in Adult is Fertility Preservation Possible? Report of Two Cases. J Obstet Gynecol Cancer Res. 2022; 7 (3) :11-11
URL: http://jogcr.com/article-1-378-en.html
1- Professor Fariba Behnamfar, M.D., Departments of Women's Oncology, School of Medicine, Isfahan university of medical Science, Iran
2- Departments of Women's Oncology, School of Medicine, Isfahan university of medical Science, Iran , maryamnazemi2012@yahoo.com
3- Departments of Pathology, School of Medicine, Isfahan university of medical Science, Iran
Abstract:   (46 Views)
Rhabdomyosarcoma(RMS)is a rare type of sarcoma.Botryoid  type being the most common .The peak incidence is the second decade.Cervical RMS is rare in adult.
We reported two cases,A 31 years old woman G1L1 referred to gynecologyst oncologyst  with abnormal vaginal bleeding.and pathology reported RMS.She received 8courses of VAC regimen for chemotherapy .3weeks after the last course she underwent conization and remnantof sarcoma was seen.Hysterectomy was done for her.She has been disease free for12month.
Case2 a 25 years old nulliparous woman presenting with abnormal vaginal bleedingوvaginal discharge.and cervical polypoid grape like lesion.Pathology reported RMS.Conization  was done.Chemotherapy with VAC regimen was done for8 courses.She has been disease free after 9years.
These two case showed that RMS can occur in rare places and at older ages.
     
Systematic Review: Case Report | Subject: Gynecology Oncology
Received: 2021/04/22 | Accepted: 2021/08/29 | Published: 2021/11/25

References
1. Ries LA, Harkins D, Krapcho M, Mariotto A, Miller BA, Feuer EJ, et al. SEER cancer statistics review, 1975-2003. 2006.
2. Kriseman ML, Wang WL, Sullinger J, Schmeler KM, Ramirez PT, Herzog CE, et al. Rhabdomyosarcoma of the cervix in adult women and younger patients. Gynecol Oncol. 2012;126(3):351-6. [DOI:10.1016/j.ygyno.2012.05.008] [PMID] [PMCID]
3. Dehner LP, Jarzembowski JA, Hill DA. Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations. Mod Pathol. 2012;25(4):602-14. [DOI:10.1038/modpathol.2011.185] [PMID] [PMCID]
4. Hosseini MS, Ashrafganjoei T, Sourati A, Tabatabeifar M, Mohamadianamiri M. Rhabdomyosarcoma of Cervix: A Case Report. Iran J Cancer Prev. 2016;9(3):e4383. [DOI:10.17795/ijcp-4383] [PMID] [PMCID]
5. Morotti RA, Nicol KK, Parham DM, Teot LA, Moore J, Hayes J, et al. An immunohistochemical algorithm to facilitate diagnosis and subtyping of rhabdomyosarcoma: the Children's Oncology Group experience. Am J Surg Pathol. 2006;30(8):962-8. [DOI:10.1097/00000478-200608000-00005] [PMID]
6. Magné N, Oberlin O, Martelli H, Gerbaulet A, Chassagne D, Haie-Meder C. Vulval and vaginal rhabdomyosarcoma in children: update and reappraisal of Institut Gustave Roussy brachytherapy experience. Int J Radiat Oncol Biol Phys. 2008;72(3):878-83. [DOI:10.1016/j.ijrobp.2008.01.034] [PMID]
7. Bradley JA, Kayton ML, Chi Y-Y, Hawkins DS, Tian J, Breneman J, et al. Treatment Approach and Outcomes in Infants With Localized Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group. International journal of radiation oncology, biology, physics. 2019;103(1):19-27. [DOI:10.1016/j.ijrobp.2018.08.017] [PMID] [PMCID]
8. Hawkins DS, Chi YY, Anderson JR, Tian J, Arndt CAS, Bomgaars L, et al. Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group. J Clin Oncol. 2018;36(27):2770-7. [DOI:10.1200/JCO.2018.77.9694] [PMID] [PMCID]
9. Sultan I, Qaddoumi I, Yaser S, Rodriguez-Galindo C, Ferrari A. Comparing adult and pediatric rhabdomyosarcoma in the surveillance, epidemiology and end results program, 1973 to 2005: an analysis of 2,600 patients. J Clin Oncol. 2009;27(20):3391-7. [DOI:10.1200/JCO.2008.19.7483] [PMID]

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