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Volume 7, Issue 3 (May & June 2022)                   J Obstet Gynecol Cancer Res 2022, 7(3): 131-143 | Back to browse issues page

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Roozbeh N, Hajian S, Darvish S, Kiani Z. The Risk Factors Affecting Low Birth Weight in Iran: An Update Systematic Review. J Obstet Gynecol Cancer Res. 2022; 7 (3) :131-143
URL: http://jogcr.com/article-1-420-en.html
1- Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
2- Department of Midwifery, Midwifery and Reproductive Health Research center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran , s.hajian@sbmu.ac.ir
3- Department of Obstetrics & Gynecology, Fellowship of Female Pelvic Floor Medicine and Reconstructive Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (888 Views)

Background & Objective: Given the significant role of low birth weight (LBW) in infant death and disability and relevant childhood diseases, the present systematic review was conducted to determine the factors affecting newborns’ birth weight in Iran.
Materials & Methods: This study systematically reviewed all the observational studies carried out in Iran between 1990 and 2021 (retrieval date: April 28, 2021) in four steps and through searches in Persian databases (including Magiran, SID, and IranDoc) and English databases (including Embase, Cochrane Library, Web of Sciences, Google Scholar, PubMed, and Scopus). All the relevant articles were searched by two researchers separately and collected using research keywords, Boolean operators, and a combination of relevant tags depending on the type of database. The quality of the articles was evaluated with 22-item Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) and Ottawa checklists, respectively.
Results: Of the 251 articles collected, 31 met the study inclusion criteria. Variables such as the mother’s age (35%), body mass index (BMI) (25%), preterm childbirth, and diagnosis with a maternal chronic disease (25%) were found to be the most common causes of LBW in the reviewed studies, by order of prevalence.
Conclusion: Based on the results of this review study and given that many of the known risk factors of LBW are preventable, the timely diagnosis, proper treatment, and follow-up of women at risk can prevent the birth of LBW infants.

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Systematic Review: Review | Subject: Obstetrics and Gynecology
Received: 2021/06/11 | Accepted: 2021/08/14 | Published: 2022/01/12

1. Cole TJ, Statnikov Y, Santhakumaran S, Pan H, Modi N, Neonatal Data Analysis U, et al. Birth weight and longitudinal growth in infants born below 32 weeks' gestation: a UK population study. Arch Dis Child Fetal Neonatal Ed. 2014;99(1):F34-40. [DOI:10.1136/archdischild-2012-303536] [PMID] [PMCID]
2. Ballot DE, Chirwa TF, Cooper PA. Determinants of survival in very low birth weight neonates in a public sector hospital in Johannesburg. BMC Pediatr. 2010;10(1):1-11. [DOI:10.1186/1471-2431-10-30] [PMID] [PMCID]
3. Callaghan WM, MacDorman MF, Rasmussen SA, Qin C, Lackritz EM. The contribution of preterm birth to infant mortality rates in the United States. Pediatrics. 2006;118(4):1566-73. [DOI:10.1542/peds.2006-0860] [PMID]
4. Kayode GA, Amoakoh-Coleman M, Agyepong IA, Ansah E, Grobbee DE, Klipstein-Grobusch K. Contextual risk factors for low birth weight: a multilevel analysis. PloS One. 2014;9(10):e109333. [DOI:10.1371/journal.pone.0109333] [PMID] [PMCID]
5. Trotman H, Bell Y. Neonatal sepsis in very low birthweight infants at the University Hospital of the West Indies. West Indian Med J. 2006;55(3):165-9. [DOI:10.1590/S0043-31442006000300007] [PMID]
6. Anthony S, den Ouden L, Brand R, Verloove-Vanhorick P, Gravenhorst JB. Changes in perinatal care and survival in very preterm and extremely preterm infants in The Netherlands between 1983 and 1995. Eur J Obstet Gynecol Reprod Biol. 2004;112(2):170-7. [DOI:10.1016/S0301-2115(03)00328-2]
7. Golestan M, Fallah R, Akhavan Karbasi S. Neonatal mortality of low birth weight infants in Yazd, Iran. Int J Reprod Biomed. 2008;6(5):205-0. [DOI:10.1016/j.earlhumdev.2008.09.065]
8. Luyckx VA, Bertram JF, Brenner BM, Fall C, Hoy WE, Ozanne SE, et al. Effect of fetal and child health on kidney development and long-term risk of hypertension and kidney disease. Lancet. 2013;382(9888):273-83. [DOI:10.1016/S0140-6736(13)60311-6]
9. Mercier C, Dunn M, Ferrelli K, Howard D, Soll R. Vermont Oxford Network ELBW Infant Follow Up Study Group. Neurodevelopmental outcome of extremely low birth weight infants from the Vermont Oxford Network: 1998-2003. Neonatology. 2010;97(4):329-38. [DOI:10.1159/000260136] [PMID] [PMCID]
10. Movsas TZ, Pinto-Martin JA, Whitaker AH, Feldman JF, Lorenz JM, Korzeniewski SJ, et al. Autism spectrum disorder is associated with ventricular enlargement in a low birth weight population. The Journal of pediatrics. 2013;163(1):73-8. [DOI:10.1016/j.jpeds.2012.12.084] [PMID] [PMCID]
11. Pilgaard K, Faerch K, Carstensen B, Poulsen P, Pisinger C, Pedersen O, et al. Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes. Diabetologia. 2010;53(12):2526-30. [DOI:10.1007/s00125-010-1917-3] [PMID]
12. Singh G, Chouhan R, Sidhu K. Maternal Factors for Low Birth Weight Babies. Med J Armed Forces India. 2009;65(1):10-2. [DOI:10.1016/S0377-1237(09)80045-2]
13. Li X, Sundquist J, Sundquist K. Parental occupation and risk of small-for-gestational-age births: a nationwide epidemiological study in Sweden. Hum Reprod. 2010;25(4):1044-50. [DOI:10.1093/humrep/deq004] [PMID] [PMCID]
14. Burdorf A, Brand T, Jaddoe VW, Hofman A, Mackenbach JP, Steegers EA. The effects of work-related maternal risk factors on time to pregnancy, preterm birth and birth weight: the Generation R Study. Occup Environ Med. 2011;68(3):197-204. [DOI:10.1136/oem.2009.046516] [PMID]
15. Rahman MM, Abe SK, Kanda M, Narita S, Rahman MS, Bilano V, et al. Maternal body mass index and risk of birth and maternal health outcomes in low- and middle-income countries: a systematic review and meta-analysis. Obes Rev. 2015;16(9):758-70. [DOI:10.1111/obr.12293] [PMID]
16. Yadav H, Lee N. Maternal factors in predicting low birth weight babies. Med J Malaysia. 2013;68(1):44-7.
17. Huang H, Coleman S, Bridge JA, Yonkers K, Katon W. A meta-analysis of the relationship between antidepressant use in pregnancy and the risk of preterm birth and low birth weight. Gen Hosp Psychiatry. 2014;36(1):13-8. [DOI:10.1016/j.genhosppsych.2013.08.002] [PMID] [PMCID]
18. Fleischer NL, Merialdi M, van Donkelaar A, Vadillo-Ortega F, Martin RV, Betran AP, et al. Outdoor air pollution, preterm birth, and low birth weight: analysis of the world health organization global survey on maternal and perinatal health. Environ Health Perspect. 2014;122(4):425-30. [DOI:10.1289/ehp.1306837] [PMID] [PMCID]
19. Chaman R, Amiri M, Raei M, Ajami ME, Sadeghian A, Khosravi A. Low birth weight and its related risk factors in northeast iran. Iran J Pediatr. 2013;23(6):701-4.
20. Azadbakht L, Kelishadi R, Saraf-Bank S, Qorbani M, Ardalan G, Heshmat R, et al. The association of birth weight with cardiovascular risk factors and mental problems among Iranian school-aged children: the CASPIAN-III study. Nutrition. 2014;30(2):150-8. [DOI:10.1016/j.nut.2013.06.005] [PMID]
21. Roozbeh N, Darvish L, Abdi F. Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal. BMC Res Notes. 2017;10(1):331. [DOI:10.1186/s13104-017-2646-1] [PMID] [PMCID]
22. Roozbeh N, Azizi M, Darvish L. Pregnancy Outcome of Abnormal Nuchal Translucency: A Systematic Review. J Clin Diagn Res. 2017;11(3):QC12-QC6. [DOI:10.7860/JCDR/2017/23755.9384] [PMID] [PMCID]
23. Roozbeh N, Nahidi F, Hajiyan S. Barriers related to prenatal care utilization among women. Saudi Med J. 2016;37(12):1319. [DOI:10.15537/smj.2016.12.15505] [PMCID]
24. Bahrami N, Soleimani MA, Rashvand F, Nia HS, Aboutorabi S, Javadi Z. Association between seasonal patterns and birth weight. Koomesh. 2012;13(4).
25. Khalilian AR, Hamta A, Farhadi R, Ranjbaran H. Investigation factors of low birth weight infants with structural equation model approach. J Mazandaran Uni Med Sci. 2012;21(86):108-14.
26. Ghavi A, Fadakar Sogheh K, Niknamy M, Kazemnejad E. Investigating the relationship between maternal lifestyle during pregnancy and low-birth-weight of term neonates. Iran J Obes Gyn Infertil. 2012;15(29):14-24.
27. Delaram M. The incidence and related factors of low birth weight. Iran J Nurs Res. 2010;23.
28. Kahnamooey Aqdam F, F; A, R; D. Relationship between maternal body mass index and birth weight of Alzahra hospital in Rasht. Journal of health and care 2009;11(2):64-70.
29. Yousefi J, Mirzadeh M, N TA. The Prevalence of LBW and Determination of Prevalence Rate and IUGR in Newborns Born in Mashhad 22 Bahman Hospital during a Year. J Med Sci. 2015;5(1):1-5.
30. FallahMS, Gholamali A,, Heidari H GB. The Study of Factors Affecting Birth Weight of Newborns in Yazd Province in 2007". Tolo-e- behdasht. 1998;7(3):57-64.
31. Younesi F, Ali; HH, Gholamali A. Examining some of the effective psychological characteristics of parents in low birth weight of infants in Fars province. Sci J Med Council IR. 2008;6(3):23-31.
32. Zahedi R, Seyed Esmaeil M, M S. Investigating the effective factors on the low birth weight in Jahrom. J Jahrom Uni Med Sci. 2008;5(3):1-9. [DOI:10.29252/jmj.]
33. Baghianimoghadam MH, Baghianimoghadam B, Ardian N, Alizadeh E. Risk factors of low birth weight and effect of them on growth pattern of children up to sixth months of life: A cross-sectional study. J Educ Health Promot. 2015;4.
34. Tootoonchi P. Low birth weight among newborn infants at Tehran hospitals. Iran J Pediatr. 2007;17(s2):186-92.
35. Eshraghian M, Abolghasemi J, Ghafari J, Rajai S. The effects of risk factor of pregnancy period on infant's weight. J Inflamm Dis. 2008;11(4):60-5.
36. Maryam A, Sedigheh Sh , Baqaee M , A K. The study of maternal predictors of low birth weight of infants. The two chapters of nursing and midwifery faculties of Guilan province. 2005;15(2):32-5.
37. Mosayebi Z, Fakhraee H, Movahedian AH. Prevalence and risk factors of low birth weight infants in Mahdieh hospital, Tehran. 2004.
38. Zahoor A. The relationship between overweight in the first pregnancy and the birth weight of the baby. Fertil Steril. 2002;3(3):33-9.
39. Raf Raf M, Mahdavi R, M; AMS, . Investigation of some factors affecting the weight gain of pregnant mothers and birth weight of infants. J Tabriz Uni Med Sci. 2002;55(2):31.
40. Garmaroudi GH, Eftekhar H., E B. Prevalence and risk factors on the low birth weight in Tehran. Payesh (Health Monitor). 2011;1(1):26-9.
41. Sha'ri S, Mohammadzadeh Z, Mostafavi F, Hasanzadeh A. Prevalence of low birth weight and determination of some risk factors in nursing homes in Isfahan. J Guilan Uni Med Sci. 2000;3(4):23.-30.
42. Tavakoli Ghouchani H, Armat MR, Mortazavi H, Ali Babaei A. The Investigation of the Relationship between Factors Influencing Birth Weight of Newborns in Bojnourd Ofogh-e- danesh. 200;6(2):15-21.
43. Salehi K, Mahmoodi Z, Kabir K, Dolatian M. Pathways of job style and preterm low birth weight. Electron Physician. 2016;8(9):2888-96. [DOI:10.19082/2888] [PMID] [PMCID]
44. Monjezi M, Rostami S, Moradi Kal Boland M, Cheraghian B. Survey of the relationship between mother's chronic diseases and low birth weight in infants, Ahvaz, South of Iran, 2014. Jundishapur J Chronic Dis Care. 2017;6(2). [DOI:10.5812/jjcdc.38259]
45. Moradi G, Khazaei Z, Esmailnasab N, Roshani D, Zokaii M, Ghaderi E, et al. The relationship between maternal diseases during pregnancy and low birth weight: a nested case-control study in rural areas of Kurdistan Province (west of Iran). Int J Pediatr. 2017;5(8):5501-14.
46. Momeni M, Danaei M, Kermani AJ, Bakhshandeh M, Foroodnia S, Mahmoudabadi Z, et al. Prevalence and Risk Factors of Low Birth Weight in the Southeast of Iran. Int J Prev Med. 2017;8:12. [DOI:10.4103/ijpvm.IJPVM_112_16] [PMID] [PMCID]
47. Karamzad N, Safiri S, Amiri S, Syedi N, Ebrahimi-Mameghani M, Moosazadeh M, et al. Predictors of low birth weight infants in the North West Province of Iran: a Case-control study. Int J Pediatr. 2016;4(6):1983-91.
48. Khorshidi M, Nooshirvanpour P, Najafi S. Incidence of low birth weight in mazandaran province, northern iran. Oman Med J. 2013;28(1):39-41. [DOI:10.5001/omj.2013.09] [PMID] [PMCID]
49. HASHEMIAN NN, Pejhan A, Rakhshani MH, Hoseini BL. The incidence of low birth weight (LBW) and small-for-gestational age (SGA) and its related factors in neonates, Sabzevar, Iran. 2014.
50. Ahmadi P, Alavimajd H, Khodakarim S, Tapak L, Kariman N, Amini P, et al. Prediction of low birth weight using Random Forest: A comparison with Logistic Regression. Arch Adv Biosci. 2017;8(3):36-43.
51. Manouchehri Torshizi E, Fathi Najafi T, Vafaee Najar A, Molkizadeh M, Larki M. Maternal Factors Associated with Low Birth Weight in Kashmar, Iran. J Midwifery Womens Health. 2021;9(1):2629-35.
52. Sarizadeh R, Dastoorpoor M, Goudarzi G, Simbar M. The association between air pollution and low birth weight and preterm labor in Ahvaz, Iran. Int J Womens Health. 2020;12:313. [DOI:10.2147/IJWH.S227049] [PMID] [PMCID]
53. Asgarian A, Sourani K, Afrashteh S, Mohammadbeigi A, Aligol M. Low birth weight incidence in newborn'neonate in Qom, Iran: Risk factors and complications. J Med Sci. 2020;40(4):162-6. [DOI:10.4103/jmedsci.jmedsci_164_19]
54. Sharifi Z, Safari E, Safari E, Ghamari E, Behgam N, Mohajeri T. Evaluation of the Relationship between Hemoglobin Level in the First and Third Trimesters of Pregnancy with Birth Weight in Pregnant Women. Health Res Policy Syst. 2020;6(1):8-15. [DOI:10.29252/hrjbaq.6.1.8]
55. Dennis JA, Mollborn S. Young maternal age and low birth weight risk: An exploration of racial/ethnic disparities in the birth outcomes of mothers in the United States. Soc Sci J. 2013;50(4):625-34. [DOI:10.1016/j.soscij.2013.09.008] [PMID] [PMCID]
56. Restrepo-Mendez MC, Lawlor DA, Horta BL, Matijasevich A, Santos IS, Menezes AM, et al. The association of maternal age with birthweight and gestational age: a cross-cohort comparison. Paediatr Perinat Epidemiol. 2015;29(1):31-40. [DOI:10.1111/ppe.12162] [PMID] [PMCID]
57. Al-Hinai M, Al-Muqbali M, Al-Moqbali A, Gowri V, Al-Maniri A. Effects of Pre-Pregnancy Body Mass Index and Gestational Weight Gain on Low Birth Weight in Omani Infants: A case-control study. Sultan Qaboos Univ Med J. 2013;13(3):386-91. [DOI:10.12816/0003260] [PMID] [PMCID]
58. Daliri S, Karimi A, Sayehmiri K, Bazyar J, Sayehmiri F. Relationship between some maternal and neonatal factors during previous pregnancies and low birth weight in Iran: A Systematic Review and Meta-analysis. Iran J Obes Gyn Infertil. 2016;19(31):23-32.
59. da Costa BR, Cevallos M, Altman DG, Rutjes AW, Egger M. Uses and misuses of the STROBE statement: bibliographic study. BMJ Open. 2011;1(1):e000048. [DOI:10.1136/bmjopen-2010-000048] [PMID] [PMCID]
60. Miletic T, Stoini E. Influence of maternal pregravid weight, height and body mass index on birth weight of male and female newborns. Coll Antropol. 2005;29(1):263-6.
61. Murakami M, Ohmichi M, Takahashi T, Shibata A, Fukao A, Morisaki N, et al. Prepregnancy body mass index as an important predictor of perinatal outcomes in Japanese. Arch Gynecol Obstet. 2005;271(4):311-5. [DOI:10.1007/s00404-004-0629-7] [PMID]
62. De Bernabé JV, Soriano T, Albaladejo R, Juarranz M, Calle MaE, Martı́nez D, et al. Risk factors for low birth weight: a review. Eur J Obstet Gynecol Reprod Biol. 2004;116(1):3-15. [DOI:10.1016/j.ejogrb.2004.03.007] [PMID]
63. Carrera JM. Ultrasonographic diagnosis of intrauterine growth restriction. Donald Sch J Ultrasound Obstet Gynecol. 2004:318.
64. Berglund SK, Westrup B, Hägglöf B, Hernell O, Domellöf M. Effects of iron supplementation of LBW infants on cognition and behavior at 3 years. Pediatrics. 2013;131(1):47-55. [DOI:10.1542/peds.2012-0989] [PMID]
65. Dasa TT, Kassie TW, Roba AA, Kelel HU. Prevalence and Determinants of Low Birth Weight in Ethiopia: A Systematic Review and Meta-Analysis. Afr J Health Sci. 2020;33(2):49-64.
66. Yimer NB, Tenaw Z, Gedefaw A. Pregnancy outcomes in Grand multiparous women: Does parity matter? A comparative study. Afr J Reprod Health. 2020;12(1):11-.
67. Han Z, Lutsiv O, Mulla S, McDonald SD, Knowledge Synthesis G. Maternal height and the risk of preterm birth and low birth weight: a systematic review and meta-analyses. J Obstet Gynaecol Can. 2012;34(8):721-46. [DOI:10.1016/S1701-2163(16)35337-3]

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