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Volume 7, Issue 3 (May & June 2022)                   J Obstet Gynecol Cancer Res 2022, 7(3): 7-7 | Back to browse issues page

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Mansour Ghanaei M, Amir Afzali S, Morady A, Mansour Ghanaie R, Asghari Ghalebin S M, Rafiei E et al . Intrauterine Growth Restriction with and without Pre-Eclampsia: Pregnancy Outcome and Placental Findings. J Obstet Gynecol Cancer Res. 2022; 7 (3) :7-7
URL: http://jogcr.com/article-1-459-en.html
Intrauterine Growth Restriction with and without Pre-Eclampsia: Pregnancy Outcome and Placental Findings
Mandana Mansour Ghanaei1 , Sude Amir Afzali2 , Ali Morady3 , Roxana Mansour Ghanaie4 , Seyed Mohammah Asghari Ghalebin2 , Elahe Rafiei5 , Roya Kabodmehri * 6
1- Reproductive Health Research Center, Department of Obstetrics and Gynecology, Alzahra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
2- Guilan University of Medical Sciences, Rasht, Iran
3- Lahijan Milad Hospital, Lahijan, Guilan, Iran
4- Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5- Razi Clinical Research Development Unit, Guilan University of Medical Science, Rasht, Iran
6- Assistant Professor of Obstetrics & Gynecology, Reproductive Health Research Center, Department of Obstetrics & Gynecology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran , royakabodmehri@yahoo.com
Abstract:   (43 Views)
Aims: The current study assessed pregnancy outcomes and pathological findings of placenta due to IUGR with or without pre-eclampsia.
Methods and Methods: This cohort study was conducted on two groups: group I was pre-eclampsia-induced Intrauterine Growth Restriction (PE-IUGR) and group ii was idiopathic Intrauterine Growth Restriction (I-IUGR). Pregnancy and neonatal outcome was evaluated in both groups. Placental assessment was also performed based on pathologic results. The data collected were compiled and analyzed by SPSS software version 21.
An analytical study was performed in two groups of PE-IUGR and I-IUGR based on T-Test (or non-parametric Mann-Whitney) and Chi-Square and Fisher's Exact Test.
Finding: The findings of this study showed that maternal age, BMI and incidence of preterm delivery as well as low birth weight were higher in the PE-IUGR group (p<0.001 in all (; and the difference was statistically significant. Additionally, the results indicated that circulatory disorders and impaired anomalies were higher in the PE-IUGR group (p>0.001).
Conclusion: According to the results of this study, placental disorders and reduced blood flow to the fetus due to placental disorders might lead to low birth weight and preterm delivery.
Keywords: Intrauterine Growth Restriction|Placenta|Pre-Eclampsia|Premature Birth ,
     
Systematic Review: Original Research | Subject: Obstetrics and Gynecology
Received: 2021/07/28 | Accepted: 2021/08/21 | Published: 2021/11/25
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