Document Type : Original Research Article
Authors
Department of Pedodontic and Preventive Dentistry, College of Dentistry, University of Baghdad, Iraq
Abstract
Background & Objective: This study's main objective was to establish physical characteristics (pH and flow rate) and dental caries experience among women with PCOS and to perform an assessment of dental caries relationship to salivary antioxidant biomarker (total antioxidant capacity and uric acid).
Materials and Methods: There was 80 women in the study (40 female with PCOS and 40 healthy female served as controls) with ages ranging from 25 to 30 years and with a range of body mass indices 18.5-24.9 (normal weight). Unstimulated saliva was obtained. Both salivary pH and flow rate were discovered immediately. After that, saliva was subjected to biochemical analysis to determine salivary TAC and UA levels using ELISA method. Dental caries diagnosis and registration were assessed using WHO in 2013.
Results: In the PCOS group, the mean salivary flow rate and pH were lower than in the control group, with a statistically significant difference (P<0.05). The salivary (TAC) and (UA) mean values were higher in the PCOS group than in the healthy females, with a statistically significant difference (P<0.05). while dental caries fractions was positively not significant correlated with total antioxidant capacity and uric acid in the study group except (DMFT) was positively significant correlated with antioxidant Parameter (TAC) (P< 0.05 ) and (DS and DMFT) were positively significant with uric acid among women with PCOS (P< 0.05).
Conclusions: Furthermore, Salivary TAC and UA were elevated in PCOS which can be used in the future as indicators for the PCOS diagnosis.
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